As undergoing pancreaticoduodenectomy at the johns hopkins hospital between 1970 and 1994 were analyzed (the last large integer resections were performed between march 1991 and april 1994). This is the largest single-institution experience reported to date. Results: the overall postoperative in-hospital mortality rate was 5%, but has been 0. 7% for the last 149 patients. The actuarial 5-year survival for all 201 patients was 21%, with a median survival of 15. 5 months. what's better viagra viagra There were 11 5-year survivors. is 200 mg of viagra too much Patients resected with negative margins (curative resections: n = 143) had an actuarial 5-year survival rate of 26%, with a median survival of 18 months, whereas those with positive margins (palliative resections; n = 58) fared significantly worse, with an actuarial 5-year survival rate of 8% and a median survival of 10 months (p < 0. 0001). Survival has improved significantly from decade to decade (p < 0. buy generic viagra online 002), with the 3-year actuarial survival of 14% in the 1970s, 21% in the 1980s, and 36% in the 1990s. Factors significantly favoring long-term survival by univariate analyses included tumor diameter < 3 cm, negative nodal status, diploid tumor dna content, tumor s phase fraction < 18%, pylorus-preserving resection, < 800 ml intraoperative blood loss, < 2 units of blood transfused, negative resection margins, and use of postoperative adjuvant chemotherapy and radiation therapy. Multivariate analyses indicated the strongest predictors of long-term survival were diploid tumor dna content, tumor diameter < 3 cm, negative nodal status, negative resection margins, and decade of resection. buy viagra Conclusions: the survival of patients with pancreatic adenocarcinoma treated by pancreaticoduodenectomy is improving. generic viagra Aspects of tumor biology, such as dna content, tumor diameter, nodal status and margin status, are the strongest predictors of outcome. viagra 2.5 mg price Pmid: 7794076 [pubmed - indexed for medline] pmcid: pmc1234702 free pmc article publication types, mesh terms, substances, grant support publication types clinical trial research support, u. discount generic viagra mg S. viagra no prescription Gov't, p. viagra 2.5 mg price H. S. buy viagra online Mesh terms actuarial analysis adenocarcinoma/genetics adenocarcinoma/mortality adenocarcinoma/pathology adenocarcinoma/surgery* adenocarcinoma/therapy aged chemotherapy, adjuvant combined modality therapy dna, neoplasm/analysis female follow-up studies humans male middle aged multivariate analysis pancreatic neoplasms/genetics pancreatic neoplasms/mortality pancreatic neoplasms/pathology pancreatic neoplasms/surgery* pancreatic neoplasms/therapy pancreaticoduodenectomy*/methods radiotherapy, adjuvant survival rate treatment outcome substances dna, neoplasm grant support r01-ca56130/ca/nci nih hhs/united states linkout - more resources full text sources lippincott williams & wilkins ovid technologies, inc. viagra 2.5 mg price Pubmed central other literature sources cos scholar universe medical pancreatic cancer - medlineplus health information supplemental content save items add to favorites loading rel. order viagra online no prescription viagra safe ace inhibitors
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Galati, B-dul Marea Unire nr.1